Peptides
CJC No DAC
Modified GRF (1–29), its growth-hormone pathway, and how its fitness evidence differs from long-acting CJC-1295 and ipamorelin blends.
Keep learning. Keep adapting.
Research notes and practical guides on supplements, nutrition, exercise, and the questions behind better training.
Peptides
61 articlesPeptides
Tesamorelin
Tesamorelin is an approved prescription peptide for excess abdominal fat in adults with HIV-associated lipodystrophy. Trials show less visceral fat in that population; it is not approved as a general weight-loss or bodybuilding drug.
Peptides
Ipamorelin
Ipamorelin stimulates a growth-hormone pulse in human testing. Claims about added muscle, fat loss, or recovery go beyond the direct trials, and practitioner injection amounts are not validated fitness doses.
Peptides
Melanotan 2
Melanotan 2 can stimulate pigmentation and has shown effects in small human studies, but it is an unapproved tanning drug with important safety concerns and no established cosmetic-use dose.
Peptides
Melanotan 1
Melanotan 1 usually refers to afamelanotide. Its approved 16 mg implant helps adults with erythropoietic protoporphyria tolerate sunlight; that medical evidence does not establish a cosmetic tanning protocol.
Peptides
Epitalon
Epitalon is a four-amino-acid peptide studied for telomere biology and possible sleep or aging effects. The clearest findings are from cells; human longevity benefits and an effective injection schedule have not been established.
Peptides
Tirzepatide
Tirzepatide is a prescription GIP/GLP-1 receptor agonist with strong randomized evidence for weight loss. Zepbound's weekly dose starts low and increases according to response and tolerability.
Peptides
Semaglutide
Semaglutide is a prescription GLP-1 receptor agonist with strong human evidence for weight management. The approved dose depends on the product, route, and indication, and is increased gradually.
Peptides
Retatrutide
Retatrutide is an investigational once-weekly peptide drug for obesity that acts on three hormone receptors. Randomized trials show substantial average weight loss, but it does not yet have an approved prescribing dose.
Peptides
KPV
KPV is a short anti-inflammatory peptide being studied for gut and skin problems. Mouse and cell studies are encouraging, while human efficacy and safe-dose information remain very limited.
Peptides
GHK-Cu
GHK-Cu is a copper-binding peptide used mainly in skin-care products. Cell and animal repair findings are promising; small topical human studies are mixed, and injectable claims do not have comparable human testing.
Peptides
TB-500
TB-500 is discussed for soft-tissue recovery because of thymosin beta-4 research, but the marketed fragment and full-length peptide are different substances. Human recovery and dose data for TB-500 itself are not established.
Peptides
BPC-157
BPC-157 has promising animal research for tissue repair and gut protection, and many users report benefits. Human studies have not yet established how much it speeds healing or which dose works best.