Peptides
CJC No DAC
Modified GRF (1–29), its growth-hormone pathway, and how its fitness evidence differs from long-acting CJC-1295 and ipamorelin blends.
Research notes and practical guides on supplements, nutrition, exercise, and the questions behind better training.
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71 articlesPeptides
Modified GRF (1–29), its growth-hormone pathway, and how its fitness evidence differs from long-acting CJC-1295 and ipamorelin blends.
Peptides
Tesamorelin is an approved prescription peptide for excess abdominal fat in adults with HIV-associated lipodystrophy. Trials show less visceral fat in that population; it is not approved as a general weight-loss or bodybuilding drug.
Peptides
Ipamorelin stimulates a growth-hormone pulse in human testing. Claims about added muscle, fat loss, or recovery go beyond the direct trials, and practitioner injection amounts are not validated fitness doses.
Peptides
Melanotan 2 can stimulate pigmentation and has shown effects in small human studies, but it is an unapproved tanning drug with important safety concerns and no established cosmetic-use dose.
Peptides
Melanotan 1 usually refers to afamelanotide. Its approved 16 mg implant helps adults with erythropoietic protoporphyria tolerate sunlight; that medical evidence does not establish a cosmetic tanning protocol.
Peptides
Epitalon is a four-amino-acid peptide studied for telomere biology and possible sleep or aging effects. The clearest findings are from cells; human longevity benefits and an effective injection schedule have not been established.
Peptides
Tirzepatide is a prescription GIP/GLP-1 receptor agonist with strong randomized evidence for weight loss. Zepbound's weekly dose starts low and increases according to response and tolerability.
Peptides
Semaglutide is a prescription GLP-1 receptor agonist with strong human evidence for weight management. The approved dose depends on the product, route, and indication, and is increased gradually.
Peptides
Retatrutide is an investigational once-weekly peptide drug for obesity that acts on three hormone receptors. Randomized trials show substantial average weight loss, but it does not yet have an approved prescribing dose.
Peptides
KPV is a short anti-inflammatory peptide being studied for gut and skin problems. Mouse and cell studies are encouraging, while human efficacy and safe-dose information remain very limited.
Peptides
GHK-Cu is a copper-binding peptide used mainly in skin-care products. Cell and animal repair findings are promising; small topical human studies are mixed, and injectable claims do not have comparable human testing.
Peptides
TB-500 is discussed for soft-tissue recovery because of thymosin beta-4 research, but the marketed fragment and full-length peptide are different substances. Human recovery and dose data for TB-500 itself are not established.
Peptides
BPC-157 has promising animal research for tissue repair and gut protection, and many users report benefits. Human studies have not yet established how much it speeds healing or which dose works best.
Supplements
Huperzine A is added to pre-workouts for focus because it slows the breakdown of acetylcholine. That biological effect is measurable, while a noticeable focus or performance benefit during workouts remains uncertain.
Supplements
Caffeine is one of the better-supported pre-workout ingredients for alertness, endurance, and some lifting performance. A body-weight-based dose helps you find a useful amount while accounting for sleep and other caffeine sources.
Supplements
PEAK ATP is an oral ATP disodium ingredient included for possible strength and fatigue-resistance benefits. Small studies have reported promising strength results; researchers are still testing how dependable the effects are and how the ingredient works.
Supplements
Taurine supports normal muscle-cell functions and may offer a small benefit in some exercise tests. The pictured pre-workout contains 1 g, an amount used in small studies, while results still differ by activity.
Supplements
L-tyrosine helps the body make brain messengers involved in attention. Pre-workouts include it for possible focus support on demanding days; research is most encouraging under stress, while routine gym benefits remain an open question.
Supplements
Betaine is used daily in some pre-workouts for possible strength support during training. A modest strength benefit has appeared in reviews, and the 2.5 g in this scoop matches a common amount used in studies.
Supplements
Alpha-GPC supplies choline for acetylcholine, a messenger involved in attention and muscle signaling. Some pre-workouts include it for focus and power; small studies offer early signals, while workout effects are still being studied.
Supplements
Beta-alanine builds muscle carnosine with daily use and can modestly support sustained hard efforts, including demanding sets and intervals. Its effect depends on the workout, and the familiar tingles are simply a side effect.
Supplements
Creatine monohydrate is a well-supported daily supplement for strength and repeated hard efforts, with a possible small added benefit for muscle size. Cognitive research is emerging, especially during severe sleep deprivation.
Supplements
L-citrulline supports nitric-oxide signaling, which is why it is popular for pre-workout blood flow and the muscle pump. Exercise studies suggest a possible small benefit, with results that vary across people and workouts.